Title : PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function.

Pub. Date : 2015 Jul 14

PMID : 26169874






1 Functional Relationships(s)
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1 The protective effects of olaparib were linked to a suppression of Th2 cytokines eotaxin, IL-4, IL-5, IL-6, IL-13, and M-CSF, and ovalbumin-specific IgE with an increase in the Th1 cytokine IFN-gamma. olaparib interleukin 13 Mus musculus