Title : Development and validation of a method for the analysis of hydroxyzine hydrochloride in extracellular solution used in in vitro preclinical safety studies.

Pub. Date : 2015 Nov 10

PMID : 26163869






1 Functional Relationships(s)
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1 In the current study, a UPLC-MS/MS method was developed and validated to quantify hydroxyzine hydrochloride in an extracellular solution used in a hERG assay in concentrations ranging from 0.01 to 10muM (4.5ng/ml-4.5mug/ml). Hydroxyzine ETS transcription factor ERG Homo sapiens