Title : Polymorphisms in PLA2G6 and PLA2G4C genes for calcium-independent phospholipase A2 do not contribute to attenuated niacin skin flush response in schizophrenia patients.

Pub. Date : 2015 Sep

PMID : 26160611






1 Functional Relationships(s)
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1 The iPLA2beta and cPLA2gamma may play an important role in niacin-mediated signaling; in addition to their major role - mediating phospholipids remodeling, which alters membrane receptors and signal transduction, they regulate the reservoir of arachidonic acid for prostaglandins synthesis. Arachidonic Acid phospholipase A2 group VI Homo sapiens