Pub. Date : 2015
PMID : 26132489
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Nicotine Metabolite Ratio (NMR, ratio of trans-3"-hydroxycotinine and cotinine), has previously been associated with CYP2A6 activity, response to smoking cessation treatments, and cigarette consumption. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 2 | We confirmed the major role that CYP2A6 plays in nicotine metabolism, and made novel findings with respect to genome-wide significance and associations with CPD, abstinence and lung cancer risk. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |