Title : Hypothalamic action of cachectin to alter pituitary hormone release.

Pub. Date : 1989 Dec

PMID : 2611689






1 Functional Relationships(s)
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1 Preinjection of indomethacin into the 3V 1 hour prior to injection of TNF completely blocked the effect on body temperature without producing an alteration in rectal temperature itself which suggests that the elevation in body temperature may be mediated by prostaglandins. Prostaglandins tumor necrosis factor Rattus norvegicus