Title : PI3K/Akt signaling mediated Hexokinase-2 expression inhibits cell apoptosis and promotes tumor growth in pediatric osteosarcoma.

Pub. Date : 2015 Aug 21

PMID : 26116768






2 Functional Relationships(s)
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1 In this study, we showed that elevated Hexokinase-2 (HK2) expression, which catalyzes the first essential step of glucose metabolism by conversion of glucose into glucose-6-phosphate, was induced by activated PI3K/Akt signaling. Glucose-6-Phosphate hexokinase 2 Homo sapiens
2 In this study, we showed that elevated Hexokinase-2 (HK2) expression, which catalyzes the first essential step of glucose metabolism by conversion of glucose into glucose-6-phosphate, was induced by activated PI3K/Akt signaling. Glucose-6-Phosphate hexokinase 2 Homo sapiens