Title : Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis.

Pub. Date : 2015 Jun

PMID : 26112945






2 Functional Relationships(s)
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1 Determination of ODC - the key enzyme of the polyamine synthesis - in the samples of experimental tumors was performed by method of Luqman S. RESULTS: Administration of DFMO or it"s combination with nor-NOHA resulted in the decrease of tumor growth rate, number and volume of lung metastases and was accompanied with reduced ODC activity in tumor tissue. Eflornithine ornithine decarboxylase, structural 1 Mus musculus
2 Determination of ODC - the key enzyme of the polyamine synthesis - in the samples of experimental tumors was performed by method of Luqman S. RESULTS: Administration of DFMO or it"s combination with nor-NOHA resulted in the decrease of tumor growth rate, number and volume of lung metastases and was accompanied with reduced ODC activity in tumor tissue. Eflornithine ornithine decarboxylase, structural 1 Mus musculus