Pub. Date : 2015 Sep
PMID : 26111938
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Elevation of .O2(-) and H2O2 might cause oxidation of tetrahydrobiopterin (BH4) to dihydrobiopterin (BH2) and subsequent uncoupling of endothelial nitric oxide synthase (eNOS) (a) thus reducing levels of nitric oxide (NO) and 3",5"-cyclic guanosine monophosphate (cGMP). | Hydrogen Peroxide | nitric oxide synthase 3, endothelial cell | Mus musculus |
| 2 | Elevation of .O2(-) and H2O2 might cause oxidation of tetrahydrobiopterin (BH4) to dihydrobiopterin (BH2) and subsequent uncoupling of endothelial nitric oxide synthase (eNOS) (a) thus reducing levels of nitric oxide (NO) and 3",5"-cyclic guanosine monophosphate (cGMP). | Hydrogen Peroxide | nitric oxide synthase 3, endothelial cell | Mus musculus |
| 3 | Generation of H2O2 by uncoupled eNOS in cerebral microvessels of Tg2576 mice is hypothetical. | Hydrogen Peroxide | nitric oxide synthase 3, endothelial cell | Mus musculus |