Title : The influence of renal insufficiency and haemodialysis on the kinetics of ciprofibrate.

Pub. Date : 1989 Dec

PMID : 2611089






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1 Under fasting conditions, ciprofibrate, was absorbed rapidly in subjects with normal renal function, and its apparent elimination half-life was approximately 81 h. Both renal clearance (0.15 ml min-1) and cumulative renal excretion (less than 7% of the administered dose) were low. ciprofibrate CD59 molecule (CD59 blood group) Homo sapiens
2 It is concluded that, from a pharmacokinetic point of view, a reduction in the dosage of ciprofibrate should be considered in patients with a glomerular filtration rate below 30 ml min-1/1.73 m2. ciprofibrate CD59 molecule (CD59 blood group) Homo sapiens