Title : Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.

Pub. Date : 2015 Aug 15

PMID : 26105196






1 Functional Relationships(s)
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Protein Name
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1 Against hCA II, all of the tested compounds were better than the standard drug especially compounds 6c, 6d, 7c and 7d (Ki = 1.1-1.7 nM) were many fold better inhibitors than AZA (Ki = 12.1 nM). Acetazolamide carbonic anhydrase 2 Homo sapiens