Title : Synergistic augmentation of ATP-induced interleukin-6 production by arsenite in HaCaT cells.

Pub. Date : 2016 Jun

PMID : 26104857






2 Functional Relationships(s)
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1 The results showed that the addition of As(III) into the medium of HaCaT cells dose dependently increased the production of IL-6 induced by extracellular ATP, although As(III) alone had no effect on IL-6 production. as(iii) interleukin 6 Homo sapiens
2 To elucidate the mechanism of the synergistic effect of As(III) on IL-6 production by extracellular ATP, we next examined the phosphorylation of p38, ERK and epidermal growth factor receptor (EGFR), since we found that these signaling molecules were stimulated by exposure to extracellular ATP. as(iii) interleukin 6 Homo sapiens