Title : Repeat Associated Non-AUG Translation (RAN Translation) Dependent on Sequence Downstream of the ATXN2 CAG Repeat.

Pub. Date : 2015

PMID : 26086378






1 Functional Relationships(s)
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1 Strong RAN translation was also observed when driving the ATXN2 sequence with the CMV promoter with ATXN2 sequence downstream of the CAG repeat truncated to 18 bp in the polyglutamine frame but not in the polyserine or polyalanine frames. polyglutamine RAN, member RAS oncogene family Homo sapiens