Title : The Potential Role of the NLRP3 Inflammasome as a Link between Mitochondrial Complex I Dysfunction and Inflammation in Bipolar Disorder.

Pub. Date : 2015

PMID : 26075098






4 Functional Relationships(s)
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Protein Name
Organism
1 Recent studies have shown that mitochondrial production of ROS and inflammation may be closely linked through a redox sensor known as nod-like receptor pyrin domain-containing 3 (NLRP3). Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens
2 Recent studies have shown that mitochondrial production of ROS and inflammation may be closely linked through a redox sensor known as nod-like receptor pyrin domain-containing 3 (NLRP3). Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens
3 Upon sensing mitochondrial release of ROS, NLRP3 assembles the NLRP3 inflammasome, which releases caspase 1 to begin the inflammatory cascade. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens
4 Upon sensing mitochondrial release of ROS, NLRP3 assembles the NLRP3 inflammasome, which releases caspase 1 to begin the inflammatory cascade. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens