Title : Studies on orally active cephalosporin esters. III. Effect of the 3-substituent on the chemical stability of pivaloyloxymethyl esters in phosphate buffer solution.

Pub. Date : 1989 Sep

PMID : 2605680






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These results show that the substituent at the C-3 position influences mainly the electronic structure of the conjugated pi-bond system (C3 = C4 - C4 = O) and consequently affects the feasibility of isomerization to the delta 2 ester, i.e., the stability to degradation. Esters complement C3 Homo sapiens