Pub. Date : 2015
PMID : 26045738
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, isorhamnetin significantly attenuated TNF-alpha-induced upregulation of ICAM-1, VCAM-1, AP-1, E-selectin and NF-kappaB expression. | 3-methylquercetin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | So, isorhamnetin could suppress TNF-alpha-induced apoptosis and inflammation by blocking NF-kappaB and AP-1 signaling in HUVECs, which might be one of the underlying mechanisms for treatment of coronary heart disease. | 3-methylquercetin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |