Title : Association of GSTP1 and RRM1 Polymorphisms with the Response and Toxicity of Gemcitabine-cisplatin Combination Chemotherapy in Chinese Patients with Non-small Cell Lung Cancer.

Pub. Date : 2015

PMID : 26028097






1 Functional Relationships(s)
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1 BACKGROUND: Previous studies showed that genetic polymorphisms of glutathione S-transferase P1 (GSTP1) were involved in glutathione metabolism and genetic polymorphisms of ribonucleotide reductase (RRM1) were correlated with DNA synthesis. Glutathione ribonucleotide reductase catalytic subunit M1 Homo sapiens