Title : The deubiquitinase ataxin-3 requires Rad23 and DnaJ-1 for its neuroprotective role in Drosophila melanogaster.

Pub. Date : 2015 Oct

PMID : 26007638






1 Functional Relationships(s)
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1 Here, we report that ataxin-3 requires its direct interaction with the ubiquitin-binding and proteasome-associated protein, Rad23 (known as hHR23A/B in mammals) in order to suppress toxicity from polyQ species in Drosophila. polyglutamine Rad23 Drosophila melanogaster