Title : Suppression of methylmercury-induced IL-6 and MCP-1 expressions by N-acetylcysteine in U-87MG human astrocytoma cells.

Pub. Date : 2015 Aug 1

PMID : 26006043






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Suppression of methylmercury-induced IL-6 and MCP-1 expressions by N-acetylcysteine in U-87MG human astrocytoma cells. Acetylcysteine interleukin 6 Homo sapiens
2 MeHg-induced expression of MCP-1 and IL-6 mRNA was reduced by 10-20% in the presence of 5mM NAC (co-treatment experiment) compared to cells treated with MeHg only. Acetylcysteine interleukin 6 Homo sapiens
3 Pre-treatment of cells with 0.5 or 5mM NAC at 0.5 or 1h and its subsequent washout before MeHg addition suppressed MCP-1 and IL-6 cytokine expressions. Acetylcysteine interleukin 6 Homo sapiens