Title : Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy.

Pub. Date : 2015

PMID : 26004625






2 Functional Relationships(s)
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1 Mechanism of copper-lowering agents in enhancing hCtr1-mediated cis-diamminedichloroplatinum (II) (cisplatin, cDDP) transport is reviewed. cddp solute carrier family 31 member 1 Homo sapiens
2 Applications of copper chelation strategy in overcoming cDDP resistance through enhanced hCtr1 expression are evaluated. cddp solute carrier family 31 member 1 Homo sapiens