Title : Beyond COX-inhibition: 'side-effects' of ibuprofen on neoplastic development and progression.

Pub. Date : 2015

PMID : 26004413






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we review the current knowledge on COX-independent effects of ibuprofen, which affect changes in gene expression or alternative splicing and act through various cell cycle- and apoptosis-regulating pathways, including beta-catenin, NF-kappaB, PPARgamma and p53. Ibuprofen tumor protein p53 Homo sapiens