Title : Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria.

Pub. Date : 2015 Sep 16

PMID : 25998538






1 Functional Relationships(s)
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1 Furthermore, alphaB-crystallin/HSPB5 decreases the staurosporine-mediated cleavage of caspase 3 through PI3K/Akt signaling preventing apoptosis of astrocytes. Staurosporine AKT serine/threonine kinase 1 Homo sapiens