Pub. Date : 2015 May 13
PMID : 25984739
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MiRNA-194 Regulates Palmitic Acid-Induced Toll-Like Receptor 4 Inflammatory Responses in THP-1 Cells. | Palmitic Acid | toll like receptor 4 | Homo sapiens |
| 2 | In this study, we used the saturated fatty acid palmitic acid (PA) to activate TLR4 signal pathway in human monocyte cells THP-1 that established an intracellular inflammatory model. | Palmitic Acid | toll like receptor 4 | Homo sapiens |
| 3 | In this study, we used the saturated fatty acid palmitic acid (PA) to activate TLR4 signal pathway in human monocyte cells THP-1 that established an intracellular inflammatory model. | Palmitic Acid | toll like receptor 4 | Homo sapiens |
| 4 | Based on this model, we also found that PA downregulated miR-194 expression with TLR4 activation. | Palmitic Acid | toll like receptor 4 | Homo sapiens |
| 5 | We conclude that miR-194 negatively regulates the TLR4 signal pathway which is activated by PA through directly negative TRAF6 expression. | Palmitic Acid | toll like receptor 4 | Homo sapiens |