Title : Serine phosphorylation and arginine methylation at the crossroads to neurodegeneration.

Pub. Date : 2015 Sep

PMID : 25979114






1 Functional Relationships(s)
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1 Emerging evidence suggests that two key post-translational modifications of polyglutamine-expanded androgen receptor, namely serine phosphorylation by protein kinase B/Akt and arginine methylation by protein arginine methyltransferases, occur at the same consensus site, are mutually exclusive, and have opposing effects on neurotoxicity. polyglutamine AKT serine/threonine kinase 1 Homo sapiens