Title : Z-ligustilide ameliorated ultraviolet B-induced oxidative stress and inflammatory cytokine production in human keratinocytes through upregulation of Nrf2/HO-1 and suppression of NF-κB pathway.

Pub. Date : 2015 Sep

PMID : 25977183






1 Functional Relationships(s)
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1 Both silencing the nuclear factor E2-related factor 2 (Nrf2) and the supplement of tin protoporphyrin IX (SnPP), a haeme oxygenase-1 (HO-1) inhibitor, cancelled the inhibitory effect of Z-lig on UVB-induced ROS upregulation in NHEKs. S-Nitroso-N-propionyl-D,L-penicillamine heme oxygenase 1 Homo sapiens