Title : Investigation of molecular mechanisms and regulatory pathways of pro-angiogenic nanorods.

Pub. Date : 2015 Jun 7

PMID : 25963768






2 Functional Relationships(s)
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1 Herein, we report for the first time that the hydrogen peroxide (H2O2), a redox signaling molecule, generated by these EHNs activates the endothelial nitric oxide synthase (eNOS) that promotes the nitric oxide (NO) production in a PI3K (phosphoinositide 3-kinase)/Akt dependent manner, eventually triggering angiogenesis. Hydrogen Peroxide nitric oxide synthase 3 Homo sapiens
2 Herein, we report for the first time that the hydrogen peroxide (H2O2), a redox signaling molecule, generated by these EHNs activates the endothelial nitric oxide synthase (eNOS) that promotes the nitric oxide (NO) production in a PI3K (phosphoinositide 3-kinase)/Akt dependent manner, eventually triggering angiogenesis. Hydrogen Peroxide nitric oxide synthase 3 Homo sapiens