Pub. Date : 2015 Jun 2
PMID : 25959673
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | COX1 and COX2 contain heme and copper redox centers, which are integrated during assembly of the enzyme. | Copper | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
2 | COA6 interacts transiently with the copper-containing catalytic domain of newly synthesized COX2. | Copper | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
3 | Our analyses define COA6 as a constituent of the mitochondrial copper relay system, linking defects in COX2 metallation to cardiac cytochrome c oxidase deficiency. | Copper | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |