Title : Characterization of a Novel Mouse Model of Alzheimer's Disease--Amyloid Pathology and Unique β-Amyloid Oligomer Profile.

Pub. Date : 2015

PMID : 25946042






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The rTg9191 mice harbor a transgene encoding the 695 amino-acid isoform of human amyloid precursor protein (APP) with the Swedish and London mutations (APPNLI) linked to familial Alzheimer"s disease, under the control of a tetracycline-response element, as well as a transgene encoding the tetracycline transactivator, under the control of the promoter for calcium-calmodulin kinase IIalpha. Tetracycline amyloid beta precursor protein Homo sapiens