Title : Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer.

Pub. Date : 2015 Apr 20

PMID : 25940539






1 Functional Relationships(s)
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1 The anticancer effect of CUDC-101 was associated with increased expression of p21 and E-cadherin, and reduced expression of survivin, XIAP, beta-catenin, N-cadherin, and Vimentin. 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide vimentin Homo sapiens