Title : Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.

Pub. Date : 2015 Jul 1

PMID : 25924878






1 Functional Relationships(s)
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1 Treatment of Cyp4a12tg mice with DOX increased systolic blood pressure (SBP; 136 +- 2 vs. 102 +- 1 mmHg; P < 0.05), and this increase was prevented by administration of 20-HEDGE, lisinopril, or losartan. Lisinopril cytochrome P450, family 4, subfamily a, polypeptide 12a Mus musculus