Pub. Date : 2016 Feb 4
PMID : 25915848
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mechanistically, PXN-mediated extracellular signal-regulated kinases (ERK) activation is responsible for TKI resistance via decreased Bcl2-interacting mediator of cell death (BIM) and increased Mcl-1 expression due to modulating their protein stabilities by phosphorylation of BIM at serine 69 and Mcl-1 at threonine 163. | Serine | mitogen-activated protein kinase 1 | Homo sapiens |
2 | Mechanistically, PXN-mediated extracellular signal-regulated kinases (ERK) activation is responsible for TKI resistance via decreased Bcl2-interacting mediator of cell death (BIM) and increased Mcl-1 expression due to modulating their protein stabilities by phosphorylation of BIM at serine 69 and Mcl-1 at threonine 163. | Serine | mitogen-activated protein kinase 1 | Homo sapiens |