Title : [Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells].

Pub. Date : 2015 Apr

PMID : 25907934






1 Functional Relationships(s)
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1 Thioridazine treatment of the cells resulted in up-regulated PDCD4 mRNA expression and down-regulated mRNA expressions of CCND1, CDK4, c-MYC, BCL2, CASPASE3, PARP1 and EIF4A, increased PDCD4 protein expression and reduced p-AKT protein expression. Thioridazine BCL2 apoptosis regulator Homo sapiens