Title : Age-related Differences in CYP3A Abundance and Activity in the Liver of the Göttingen Minipig.

Pub. Date : 2015 Nov

PMID : 25892190






2 Functional Relationships(s)
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1 The CYP3cide and ketoconazole inhibition, and testosterone and midazolam reduction of Luciferin-IPA metabolism in minipig liver microsomes substantiate that Luciferin-IPA is metabolized by CYP3A in minipigs. luciferin-ipa cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 A positive correlation was found between CYP3A abundance and biotransformation of Luciferin-IPA (Pearson r = 0.863; p < 0.0001). luciferin-ipa cytochrome P450 family 3 subfamily A member 4 Homo sapiens