Title : Candesartan restores pressure-induced vasodilation and prevents skin pressure ulcer formation in diabetic mice.

Pub. Date : 2015 Feb 18

PMID : 25888905






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1 The present study examines whether the AT1R blocker candesartan (1) has a beneficial effect on diabetes-induced alteration of pressure-induced vasodilation (PIV, a cutaneous physiological neurovascular mechanism which could delay the occurrence of tissue ischemia), and (2) could be protective against skin pressure ulcer formation. candesartan angiotensin II, type I receptor-associated protein Mus musculus