Pub. Date : 2015 Mar 12
PMID : 25888745
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | INTRODUCTION: The objective of the present study was to evaluate the capacity of a tissue-engineered complex of human osteoprotegerin (hOPG)-transfected periodontal ligament stem cells (PDLSCs) seeding on beta-tricalcium phosphate (beta-TCP) to regenerate alveolar bone defects in New Zealand rabbits. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |
| 2 | INTRODUCTION: The objective of the present study was to evaluate the capacity of a tissue-engineered complex of human osteoprotegerin (hOPG)-transfected periodontal ligament stem cells (PDLSCs) seeding on beta-tricalcium phosphate (beta-TCP) to regenerate alveolar bone defects in New Zealand rabbits. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |
| 3 | INTRODUCTION: The objective of the present study was to evaluate the capacity of a tissue-engineered complex of human osteoprotegerin (hOPG)-transfected periodontal ligament stem cells (PDLSCs) seeding on beta-tricalcium phosphate (beta-TCP) to regenerate alveolar bone defects in New Zealand rabbits. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |
| 4 | INTRODUCTION: The objective of the present study was to evaluate the capacity of a tissue-engineered complex of human osteoprotegerin (hOPG)-transfected periodontal ligament stem cells (PDLSCs) seeding on beta-tricalcium phosphate (beta-TCP) to regenerate alveolar bone defects in New Zealand rabbits. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |
| 5 | The histological observation and histomorphometric analysis showed that the hOPG-transfected PDLSCs/beta-TCP complex exhibited an earlier mineralization and more bone formation inside the scaffold than control, beta-TCP, and PDLSCs/beta-TCP complexes. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |
| 6 | The histological observation and histomorphometric analysis showed that the hOPG-transfected PDLSCs/beta-TCP complex exhibited an earlier mineralization and more bone formation inside the scaffold than control, beta-TCP, and PDLSCs/beta-TCP complexes. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |
| 7 | The histological observation and histomorphometric analysis showed that the hOPG-transfected PDLSCs/beta-TCP complex exhibited an earlier mineralization and more bone formation inside the scaffold than control, beta-TCP, and PDLSCs/beta-TCP complexes. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |
| 8 | CONCLUSIONS: The present study demonstrated the feasibility of beta-TCP scaffolds for primary PDLSC culture and expression of hOPG gene in vitro and in vivo, and hOPG-transfected PDLSCs could serve as a potential cell source for periodontal bone regeneration, which may shed light on the potential of systemic hOPG gene therapy in combination with PDLSC tissue engineering as a good candidate in periodontal tissue engineering for alveolar bone regeneration. | beta-tricalcium phosphate | TNF receptor superfamily member 11b | Homo sapiens |