Title : β₁-adrenoceptor stimulation promotes LPS-induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation.

Pub. Date : 2015 Mar 9

PMID : 25887954






1 Functional Relationships(s)
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1 DOB also up-regulated TNF-alpha expression, decreased Bcl-2 levels, promoted Bax translocation to mitochondria, mitochondrial membrane potential loss and cytochrome c release as well as IkappaBalpha, p38 MAPK, JNK and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) phosphorylation in LPS-treated cardiomyocytes. Dobutamine BCL2-associated X protein Mus musculus