Pub. Date : 2016 Jan
PMID : 25876056
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | However, N-acetylcysteine (NAC), a scavenger of ROS, prevented the increase of ROS generation, attenuated the phosphorylation of the above kinases, and decreased the NF-kappaB activation as well as the expression of ICAM-1 and VCAM-1. | Reactive Oxygen Species | vascular cell adhesion molecule 1 | Homo sapiens |
2 | These findings suggest PM2.5 -induced ROS may function as signaling molecules triggering ICAM-1 and VCAM-1 expressions through activating the ERK/AKT/NF-kappaB-dependent pathway, and further promoting monocyte adhesion to endothelial cells. | Reactive Oxygen Species | vascular cell adhesion molecule 1 | Homo sapiens |