Title : Design and synthesis of 3-(3-((9H-carbazol-4-yl)oxy)-2-hydroxypropyl)-2-phenylquinazolin-4(3H)-one derivatives to induce ACE inhibitory activity.

Pub. Date : 2015

PMID : 25874328






1 Functional Relationships(s)
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1 To render support to the experimental results, a series of quinazolinone derivatives were docked into active site of ACE and identified the probable binding modes compared to Lisinopril. Quinazolinones angiotensin I converting enzyme Homo sapiens