Title : Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing.

Pub. Date : 2015 Jun 3

PMID : 25866054






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing. Polyethyleneimine CD274 molecule Homo sapiens
2 This study aims to block PD-1/PD-L1 interactions by delivering PD-L1 siRNA, using various folic acid (FA)-functionalized polyethylenimine (PEI) polymers, to SKOV-3-Luc EOC cells, and investigate the sensitization of the EOC cells to T cell killing. Polyethyleneimine CD274 molecule Homo sapiens