Pub. Date : 2015 Jan-Mar
PMID : 25864748
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study was undertaken to analyze whether disrupting the microtubule cytoskeleton by colchicine modulates transcriptional levels of MEFV, NF-kappaB p65, NLRP3, HMGB1, and caspase-3 in neutrophils from patients with familial Mediterranean fever (FMF) and healthy subjects. | Colchicine | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | In the present study, colchicine caused increased expression of NLRP3 (p=0.007) and MEFV (p=0.03), but had no effect on caspase-3, NF-kappaB p65 and HMGB1 genes in healthy neutrophils. | Colchicine | NLR family pyrin domain containing 3 | Homo sapiens |