Title : A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway.

Pub. Date : 2015 Sep

PMID : 25864108






2 Functional Relationships(s)
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1 Results indicated that treatments of IOMM-Lee and CH157MN meningioma cells with Limonin, Tangeritin, Zerumbone, 6-Gingerol, Ganoderic Acid A, and Ganoderic Acid DM induced apoptosis with enhanced phosphorylation of glycogen synthase kinase 3 beta (GSK3beta) via inhibition of the Wnt5/beta-catenin pathway. gingerol glycogen synthase kinase 3 beta Homo sapiens
2 Results indicated that treatments of IOMM-Lee and CH157MN meningioma cells with Limonin, Tangeritin, Zerumbone, 6-Gingerol, Ganoderic Acid A, and Ganoderic Acid DM induced apoptosis with enhanced phosphorylation of glycogen synthase kinase 3 beta (GSK3beta) via inhibition of the Wnt5/beta-catenin pathway. gingerol glycogen synthase kinase 3 beta Homo sapiens