Title : GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases.

Pub. Date : 2015 Oct

PMID : 25858032






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sorafenib/regorafenib and the multi-kinase inhibitor pazopanib (Votrient) interacted with sildenafil (Viagra) to further rapidly reduce GRP78 levels in eukaryotes and as single agents to reduce Dna K levels in prokaryotes. Sildenafil Citrate heat shock protein family A (Hsp70) member 5 Homo sapiens
2 Sorafenib/regorafenib and the multi-kinase inhibitor pazopanib (Votrient) interacted with sildenafil (Viagra) to further rapidly reduce GRP78 levels in eukaryotes and as single agents to reduce Dna K levels in prokaryotes. Sildenafil Citrate heat shock protein family A (Hsp70) member 5 Homo sapiens