Pub. Date : 2015 Oct
PMID : 25857363
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HS alone and ASA + HS caused a major up-regulation of HSP70 mRNA in the first 2 h, while HSP70 protein increased gradually and was especially abundant from 2 h to 24 h. Regarding Bcl-2, all treatments rendered similar results: gene expression was down-regulated in the first 2 h, after which there was protein elevation (12-48 h after HS). | Aspirin | BCL2 apoptosis regulator | Homo sapiens |
| 2 | In conclusion, 0.4 mM ASA + HS does not act as a co-inducer of HSP70 in HepG2 cells, but promotes Bcl-2 protein expression during prolonged treatment. | Aspirin | BCL2 apoptosis regulator | Homo sapiens |