Title : Lamotrigine Reduces β-Site AβPP-Cleaving Enzyme 1 Protein Levels Through Induction of Autophagy.

Pub. Date : 2015

PMID : 25854934






1 Functional Relationships(s)
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1 Chronic LTG treatment rescues the suppressed long-term potentiation, loss of spines and cognitive deficits in AbetaPP/PS1 mice, known to overexpress a chimeric mouse/human mutant amyloid-beta protein precursor (AbetaPP) and a mutant human presenilin 1 (PS1). Lamotrigine presenilin 1 Mus musculus