Title : Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function.

Pub. Date : 2015 May 22

PMID : 25851902






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We conclude that modification of the functional groups attached to the D-ring of the hydrocortisone steroid molecule produces compounds with altered structure-function GR agonist activity with decreased impact on insulin secretion and reduced adipogenic potential but with preservation of anti-inflammatory activity. Steroids insulin Homo sapiens