Pub. Date : 2015 Sep
PMID : 25846733
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This study suggested that long-term endocrine therapy facilitates leptin and ObRb overexpression in breast cancer cells, which attenuates the inhibitory effect of tamoxifen by activating both the ERK1/2 and STAT3 signaling pathways and upregulating CCND1 gene expression. | Tamoxifen | cyclin D1 | Homo sapiens |