Title : Attenuation of renovascular hypertension by cyclooxygenase-2 inhibitor partly through ANP release.

Pub. Date : 2015 Jul

PMID : 25846103






1 Functional Relationships(s)
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1 Chronic treatment with nimesulide or NS-398 (5 mg/kg/day) for 3 weeks lowered high blood pressure and cardiac hypertrophy with decreased expression levels of cardiac hypertrophy markers [atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP)], Ang type 1 receptor, urotensin II, and urotensin II receptor in 2K1C rats. nimesulide urotensin 2 Rattus norvegicus