Title : Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.

Pub. Date : 2015 Aug

PMID : 25840272






1 Functional Relationships(s)
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1 Simvastatin induced dose-dependent apoptosis in leiomyoma cells as measured by a fluorometric caspase-3 activity assay, and inhibited proliferation as demonstrated by an (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay (both were significant at 5 and 10 muM). Simvastatin latexin Homo sapiens