Title : Aromatase expression increases the survival and malignancy of estrogen receptor positive breast cancer cells.

Pub. Date : 2015

PMID : 25837259






2 Functional Relationships(s)
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1 Furthermore, treatment with the aromatase substrate, testosterone, inhibited suspension culture-induced apoptosis whereas an aromatase inhibitor attenuated the effect of testosterone suggesting that suspended circulating ERalpha positive breast cancer cells may up-regulate intracrine estrogen activity for survival. Testosterone estrogen receptor 1 Homo sapiens
2 Furthermore, treatment with the aromatase substrate, testosterone, inhibited suspension culture-induced apoptosis whereas an aromatase inhibitor attenuated the effect of testosterone suggesting that suspended circulating ERalpha positive breast cancer cells may up-regulate intracrine estrogen activity for survival. Testosterone estrogen receptor 1 Homo sapiens