Title : The modulation of nicotinic acetylcholine receptors on the neuronal network oscillations in rat hippocampal CA3 area.

Pub. Date : 2015 Mar 26

PMID : 25810076






2 Functional Relationships(s)
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1 These results demonstrate that nicotine modulates gamma oscillations via alpha7 and alpha4beta2 nAChR as well as NMDA activation, suggesting that nAChR activation may have a therapeutic role for the clinical disorder such as schizophrenia, which is known to have impaired gamma oscillation and hypo-NMDA receptor function. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus
2 These results demonstrate that nicotine modulates gamma oscillations via alpha7 and alpha4beta2 nAChR as well as NMDA activation, suggesting that nAChR activation may have a therapeutic role for the clinical disorder such as schizophrenia, which is known to have impaired gamma oscillation and hypo-NMDA receptor function. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus