Title : Effects of Silencing Heme Biosynthesis Enzymes on 5-Aminolevulinic Acid-mediated Protoporphyrin IX Fluorescence and Photodynamic Therapy.

Pub. Date : 2015 Jul-Aug

PMID : 25809721






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 PBGS and PBGD are the first two cytosolic enzymes involved in PpIX biosynthesis, and FECH is the enzyme responsible for converting PpIX to heme. protoporphyrin IX aminolevulinate dehydratase Homo sapiens
2 PBGS and PBGD are the first two cytosolic enzymes involved in PpIX biosynthesis, and FECH is the enzyme responsible for converting PpIX to heme. protoporphyrin IX aminolevulinate dehydratase Homo sapiens
3 Silencing PBGS or PBGD significantly reduced ALA-stimulated PpIX fluorescence, whereas silencing FECH elevated basal and ALA-stimulated PpIX fluorescence. protoporphyrin IX aminolevulinate dehydratase Homo sapiens